An extremely long and detailed discussion from Jose-Luis Jimenez of how, exactly, the science of airborne transmission of disease via 5-micron infective droplets wound up wrong, and remained incorrect for much of modern medicine, culminating in the disastrous treatment of COVID-19
Justin Mason's Weblog Posts
This nails the issue with housing in Ireland:
The Government has been called on to do something to stop this. Even Fianna Fáil politicians have come out crying crocodile tears of outrage. But the truth is the investor purchase of housing in Ireland on a major scale is actually Government policy and has been for the last decade. The Government does not actually want you to be able to buy or rent an affordable home. They have created an unaffordable housing system that is focused on delivering housing as an investment asset, not a home.[…] This current crisis has been brewing for a long time. It goes back to the Celtic Tiger days of the late 1990s and early 2000s when the Fianna Fáil-PD Governments encouraged the shift from housing to be treated as a home, to people buying it up as an investment asset. They told people to speculate in the property market and gave tax breaks for landlords to buy a second, or third, home to rent out. These became the ‘buy-to-let’ investors. The banks lent out massively which added fuel to the fire of rising housing prices, and the inevitable crash happened in 2008 and 2009. As their response to the disaster they had created, Fianna Fáil turned to global ‘vulture’ funds to buy up the bad loans and failed housing projects. They set up the ‘bad bank’ NAMA, which went on, under the Fine Gael Government from 2011 to the current day, to sell off (at a discount) huge land banks and billions of euro worth of properties to vulture and real estate investment funds.
Nice walkthrough of rooting and extending a bit of IOT hardware
It’s a depressing read, as ever. Ulster Unionism is a mess, is falling apart, and is vulnerable to being taken over by the paramilitaries:
“Unionism is losing power and control. It needs leaders who have the skill to say, look, we have cards to play and if we are sensible we can save this place. Instead, Arlene said if there was a united Ireland she’d leave. People are left feeling unappeased but it is not a definite thing. It is more a kind of grief or sense they have lost something intangible. It is about shattered dreams.”
“Nuke tweets in one click” —
Don’t like a bad tweet? Block the tweet, its author, and every single person who liked it—in one click.Genius.
Here’s the best bit:
Tesla patched the vulnerabilities with an update pushed out in October 2020, and it has reportedly stopped using ConnMan. Intel was also informed since the company was the original developer of ConnMan, but the researchers said the chipmaker believed it was not its responsibility. The researchers learned that the ConnMan component is widely used in the automotive industry, which could mean that similar attacks can be launched against other vehicles as well. Weinmann and Schmotzle turned to Germany’s national CERT for help in informing potentially impacted vendors, but it’s currently unclear if other manufacturers have taken action in response to the researchers’ findings.Great job, Intel….
Solid paper in PLOS – ‘Validation testing to determine the sensitivity of lateral flow testing for asymptomatic SARS-CoV-2 detection in low prevalence settings: Testing frequency and public health messaging is key’:
Our data show that the Innova LFD can successfully detect SARS-CoV-2 infection in people with a viral titre above approximately 100 viral copies/ml. However, as determined at our site using the ThermoFisher COVID-19 TaqPath assay, it is incapable of detecting infection at comparable PCR Ct values of 30 and over. These levels of infection are indicative of very early or very late stages of infection, and as such, we would strongly recommend that LFD testing is used to screen people at very regular frequency and that a negative result should not be used to determine that someone is free from SARS-CoV-2 infection.IMO ‘very regular frequency’ is the key detail here. Single LFA rapid tests, alone, are not useful as a simple replacement for PCR tests.
If you visit the west of Ireland or Achill, you can still see the traces of booleying today. Fascinating part of Irish rural history:
by the 1800s, it was mostly young people and teenage girls especially who had the job of looking after cows at these seasonal ‘boolies’. This gave rise to a vibrant but now largely forgotten cultural scene in Ireland’s uplands. Oral history collected in the 1930s and 1940s in Connemara, Mayo, Donegal, and the Galtee Mountains makes clear that booleying facilitated the transmission of a lot of important cultural knowledge. One man from Cloch Cheannaola in Donegal states that his mother had learned her songs from other dairymaids in the hills, while another account from Iorras Aintheach in Galway outlines how the girls not only sang but played musical instruments and danced as well. [….] The small degree of independence which young women gained as participants in booleying was sometimes missed later on in life. There is an unmistakeable sense of loss in songs like Na Gamhna Geala and Aililiú na Gamhna, in which married women reminisce about their time looking after cows and calves in the hills.
Hard not to sympathise with this take —
I’ve had to develop a special radar for reading product pages now: a mounting feeling of dread as a promising technology is introduced while I inevitably arrive at the buried lede: it’s more crypto bullshit. Cryptocurrency is the multi-level marketing of the tech world. “Hi! How’ve you been? Long time no see! Oh, I’ve been working on this cool distributed database file store archive thing. We’re doing an ICO next week.” Then I leave. Any technology which is not an (alleged) currency and which incorporates blockchain anyway would always work better without it. There are hundreds, perhaps thousands, of cryptocurrency scams and ponzi schemes trussed up to look like some kind of legitimate offering. Even if the project you’re working on is totally cool and solves all of these problems, there are 100 other projects pretending to be like yours which are ultimately concerned with transferring money from their users to their founders. Which one are investors more likely to invest in? Hint: it’s the one that’s more profitable. Those promises of “we’re different!” are always hollow anyway. Remember the DAO? They wanted to avoid social arbitration entirely for financial contracts, but when the chips are down and their money was walking out the door, they forked the blockchain.
An exhaustive copy of the official Sites and Monuments Record annotated on Google Maps (via ITS Slack)
The precise molecular mechanisms connecting regular activity to improved health have been unclear. A study published April 14 in Science Advances makes major gains in this understanding. Building off previous work on single bouts of exercise, researchers at Ghent University in Belgium found that when humans perform long-term training, histamine receptors are activated, improving a variety of cardiometabolic risk factors, from insulin sensitivity to aerobic capacity and blood vessel health. “It’s awesome, it’s a very cool paper,” says University of Oregon exercise physiologist John Halliwill, who was not involved in the study. “This is one of a few studies out there finally looking at these molecular transducers, and this is the only one out there on histamine that showed that it has this lasting impact on how we adapt to exercise. . . . It’s not just a signal associated with allergies and asthma, wound healing. It seems to have a hand in everything related to exercise, which is quite amazing.”
attempting to estimate the carbon footprint of cloud computing at AWS, by estimating the power consumption of individual EC2 instances running a workload.
The numbers are in, in this _Science_ paper —
Cases of SARS-CoV-2 infection in Manaus, Brazil, resurged in late 2020, despite previously high levels of infection. Genome sequencing of viruses sampled in Manaus between November 2020 and January 2021 revealed the emergence and circulation of a novel SARS-CoV-2 variant of concern. Lineage P.1, acquired 17 mutations, including a trio in the spike protein (K417T, E484K and N501Y) associated with increased binding to the human ACE2 receptor. Molecular clock analysis shows that P.1 emergence occurred around mid-November 2020 and was preceded by a period of faster molecular evolution. Using a two-category dynamical model that integrates genomic and mortality data, we estimate that P.1 may be 1.7–2.4-fold more transmissible, and that previous (non-P.1) infection provides 54–79% of the protection against infection with P.1 that it provides against non-P.1 lineages. Enhanced global genomic surveillance of variants of concern, which may exhibit increased transmissibility and/or immune evasion, is critical to accelerate pandemic responsiveness.
Some context — European telcos no longer operate their equipment:
As an icebreaker, [telco operators] were asked if they thought the Chinese could eavesdrop through “backdoors” in Huawei equipment. Every single hand went up. One of the bankers then asked, for balance, if they thought the US could access communications through key Cisco equipment. “All the hands went straight back up without hesitation” [….] In a modern telecommunications service provider, new equipment is deployed, configured, maintained and often financed by the vendor. Just to let that sink in, Huawei (and their close partners) already run and directly operate the mobile telecommunication infrastructure for over 100 million European subscribers. The host service provider often has no detailed insight in what is going on, and would have a hard time figuring this out through their remaining staff. Rampant outsourcing has meant that most local expertise has also left the company, willingly or unwillingly.(via ITS slack)
“The evidence supporting airborne transmission is overwhelming, and evidence supporting large droplet transmission is almost non-existent” (Greenhalgh et al., Lancet, 2021) (via Daniel Lemire)
France’s official “Repairability Index” site
Very impressive level of detail here
This is chilling:
I love tech. But watching it intersect with a Hindu nationalist government trying to crush dissent, choke a free press, and destroy a nation’s secular ethos doesn’t feel like something I bought a ticket to. Writing about technology from India now feels like having a front-row seat to the country’s rapid slide into authoritarianism. “It’s like watching a train wreck while you’re inside the train,” I Slacked my boss in November.
This is the best news to happen in Ireland’s emissions situation for a while! The ESB plan to turn off the highly polluting coal power station at Moneypoint, switching it to be a hub for offshore wind energy, including energy storage using hydrogen. Moneypoint has massive connections to the Irish grid, and the amount of available wind power on the west coast is simply huge. Great stuff!
Using DD-WRT to turn off the internet for certain devices during night-time hours
‘[River] wanted to use a Raspberry Pi to bring the fans into his home automation system, but the Raspberry Pi doesn’t have a 304.2 MHz radio. What it does have is user-programmable GPIO and the rpitx package, which converts a GPIO pin into a basic radio transmitter. Of course, the Pi’s GPIO pin’s aren’t long enough to efficiently transmit at 304.2 MHz, so [River] added a proper antenna, as well as a low-pass filter to clean up the transmitted signal. The rpitx package supports OOK out of the box, so [River] was quickly able get the Pi controlling his fan in no time’
Zeynep Tufekci hits the nail on the head here — 3 particular factors were wilfully overlooked in Western countries’ early response to the COVID pandemic:
Put all three together: airborne transmission, clusters driving the epidemic, and presymptomatic transmission. Not only do we get a clear and consistent picture of many things that have happened since, we also get the mitigation strategy. Further, all three dimensions support each other: transmission from people not (yet) coughing or sneezing very much argues in favor of aerosol transmission, which explains how large clusters can be driving the epidemic and how transmission in a situation like that ship can occur. And the mitigation and other strategies become clear: pay attention to clusters and ventilation, universal masks, different policies for indoors and outdoors, etc.
Holy cow this could have been pretty serious:
A software mistake caused a Tui flight to take off heavier than expected as female passengers using the title “Miss” were classified as children, an investigation has found. The departure from Birmingham airport to Majorca with 187 passengers on board was described as a “serious incident” by the Air Accidents Investigation Branch (AAIB). An update to the airline’s reservation system while its planes were grounded due to the coronavirus pandemic led to 38 passengers on the flight being allocated a child’s “standard weight” of 35kg as opposed to the adult figure of 69kg. This caused the load sheet – produced for the captain to calculate what inputs are needed for take-off – to state that the Boeing 737 was more than 1,200kg lighter than it actually was.
Excellent thread on privacy and security of the proposed Digital Green Certificate for intra-EU safe travel during the COVID-19 pandemic, from Carmela Troncoso. tl;dr:
My conclusion is: this is an immature design of an extremely complex infrastructure with no guaranteed security. The proposed scheme is likely to go down the slippery slope of discrimination and surveillance. I’d like to end reminding my wild thought: Given that fraud is possible anyway, a simple paper-based solution with enough protection to deter cheating may be sufficient to get us through this summer, avoiding long-term consequences.
Allow Minecraft Bedrock Edition clients on mobile devices, Switch, PS4 and XBox to connect to your Java edition Minecraft server. Works particularly nicely as a plugin in a PaperMC server — will definitely give this a go and see how the kids get on….
Official guidance from the CDC is toning down the “bleach everything!” messaging:
People can be infected with SARS-CoV-2 through contact with surfaces. However, based on available epidemiological data and studies of environmental transmission factors, surface transmission is not the main route by which SARS-CoV-2 spreads, and the risk is considered to be low. The principal mode by which people are infected with SARS-CoV-2 is through exposure to respiratory droplets carrying infectious virus. In most situations, cleaning surfaces using soap or detergent, and not disinfecting, is enough to reduce risk. Disinfection is recommended in indoor community settings where there has been a suspected or confirmed case of COVID-19 within the last 24 hours. The risk of fomite transmission can be reduced by wearing masks consistently and correctly, practicing hand hygiene, cleaning, and taking other measures to maintain healthy facilities.Can we tone down the cleanliness theatre now?
The short version is this: we think about 1% of applications and traffic “out there” are still using TLS1.0/TLS1.1. Given where browsers are at, I think this percentage is an under-estimate of the usage on Java applications – I suspect it’s even higher there. When we dig in with customers “Why are you still using TLS1.0 or TLS1.1” the most common reasons are legacy appliances and applications. Think of hardware load balancers that were never updated, or can’t be, to support TLS1.2 or better. Compliance mandated traffic inspection devices that force TLS1.0 in certain industries are another reason. For these applications, the change will break them, and they’ll get a low-level exception. The users can re-enable TLS1.0 and TLS1.1, but they may suffer an outage because they likely weren’t expecting a breaking change low in the networking stack.
oh god this brings back painful memories —
On a particularly large deployment, I eventually had to layer in a second pgbouncer tier. One tier ran on the application servers and another tier on the database servers. Altogether it aggregated connections for around 1 million client processes. Tuning it was 40% dark art, 40% brute force, and 10% pure luck.Amazing to see that these issues are still something that Postgres users have to worry about :)
Good article on the topic of COVID-19 airborne transmission, with some decent graphics and charts
This is going to be one of the big scandals of COVID-19, when we get around to looking back from a position of safety in the future:
On 28 March 2020, two months after the WHO had declared COVID-19 a global health emergency, the agency broadcast a public-health message on Twitter and Facebook. “FACT: #COVID19 is NOT airborne,” it said, labelling claims to the contrary as misinformation. But evidence quickly established that the virus is transmitted by air, and researchers roundly criticized the agency. The WHO updated its advice on SARS-CoV-2 transmission three months later, acknowledging the possibility that airborne transmission might occur in some community settings. Airborne transmission in “crowded and inadequately ventilated spaces over a prolonged period of time with infected persons cannot be ruled out”, the updated advice says. Yuguo Li, a building environment engineer at the University of Hong Kong, says that he is disappointed it took the WHO and other health authorities so long. “We would have saved a lot of people” if airborne transmission was recognized earlier, he says.
Keith Dawson has written up a great summary of a paper by Dr. Zoë Hyde:
The general perception and belief for the last year has been that children are less likely than adults to be infected with SARS-CoV-2. A new paper in the journal Clinical Infectious Diseases casts serious doubt on this assumption. The author of that paper, Zoë Hyde of the University of Western Australia, argues that there are two principal reasons why the myth of a lower attack rate in children developed: we don’t test kids much, and they may only be infectious for a very short window of time. The CDC’s stance on kids and Covid seems to be overly sanguine. The metric used in their paper is hospitalization rate. It is true that hospitalization rates for teenagers and younger people are extremely low, but that may not be strongly indicative of infection rate. Kids’ infections are more likely to result in a mild or even asymptomatic case of Covid-19 — about twice as likely as for adults, according to Hyde. Combine this fact with the US bias towards testing only once symptoms appear, and you can see how this could contribute to an undercount of childhood cases. Compounding the dearth of testing is the (fairly robust) finding that, when infected, children may be shedding virus for a shorter time than adults: only two days on average, compared to five days for adults. So kids are more than twice as likely to show up PCR-negative even in the rare instances in which they are tested. Looking at seroprevalence surveys, Hyde cites studies from Italy and Brazil pointing to similar levels of children and adults who have antibodies indicating they have recovered from the disease. (In the Italian study from last year, children’s seroprevalence was even higher than that of the oldest adults, the result of what Hyde calls “survivorship bias” — i.e., the older people who got Covid-19 mostly died.) The hosts on This Week in Virology went over Hyde’s paper in last week’s podcast, TWiV #731. If you can spare the time, listen to 11 minutes’ worth of their discussion beginning at 23:33. One compelling point the TWiV team brought out: children are not immune from long Covid. A UK study found that 12.9% of kids had symptoms weeks after clearing the disease, compared with 22% of adults. The belief that children don’t get infected much should no longer be used as an argument for why schools ought to be reopened.
Turns out they accidentally released some charts back in Feb, modelling vaccination/reopening scenarios — these were probably used in private briefings to the cabinet, and not intended for public consumption (via Andrew Flood)
Well done, Slovakia — massive decrease in prevalence after 2 rounds of mass testing.
Slovakia conducted multiple rounds of population-wide rapid antigen testing for SARS-CoV-2 in late 2020, combined with a period of additional contact restrictions. Observed prevalence decreased by 58% (95% CI: 57-58%) within one week in the 45 counties that were subject to two rounds of mass testing, an estimate that remained robust when adjusting for multiple potential confounders. Adjusting for epidemic growth of 4.4% (1.1-6.9%) per day preceding the mass testing campaign, the estimated decrease in prevalence compared to a scenario of unmitigated growth was 70% (67-73%). Modelling indicated that this decrease could not be explained solely by infection control measures, but required the additional impact of isolation and quarantine of household members of those testing positive.
Testcontainers is a Java library that supports JUnit tests, providing lightweight, throwaway instances of common databases, Selenium web browsers, or anything else that can run in a Docker container.
Lovely little service to draw a map with ridgelines, Joy Division “Unknown Pleasures” style (via Nelson)
‘tl;dr: The time when Microsoft banned my entire country for cheating at Club Bing.’ This is a great story — though it must have been driving the MS Asirra anti-abuse team up the wall. Quite interesting to hear about low-cost/grassroots ways to accomplish some of the tech tasks, e.g. instead of firing up a farm of EC2 instances to crack a Captcha, he farmed out that work using thumbdrives, manually distributed to his friends.
‘The club’s name is synonymous with idiocy in Africa’s most populous nation. How on earth did this happen?’ — what a great story! (via Ben)
Interesting blog post from Nelson about Speedify, a proprietary multipath VPN service to bond two internet links to improve reliability
Amazing well-preserved human footprints from between 4200 and 4600 years ago:
The Centro Nacional de Investigación sobre la Evolución Humana (CENIEH) has participated in chapter 17, which covers the prints of bare feet preserved in the soft floor sediment of Palomera Cave in the Ojo Guareña Karst Complex (Merindad de Sotoscueva, Burgos, Spain). These footprints, ascribed to traces left by about ten individuals who explored the caves between 4200 and 4600 years ago, were discovered in 1969 by Grupo Espeleológico Edelweiss (GEE) at the Sala y Galerías de las Huellas site, some 1200 m from the entrance to Palomera Cave. The fragility of the footprints and their environment meant it was not possible to study them, and doing so has had to await the development of the new non-invasive teledetection techniques.
Great essay on the shitfest that is NFTs and cryptoart:
During unprecedented temperature increases, sea level rise, the total loss of permanent sea ice, widespread species extinction, countless severe weather events, and all the other hallmarks of total climate collapse, this kind of gleeful wastefulness is, and I am not being hyperbolic, a crime against humanity.
Prof. Akiko Iwasaki on Twitter: “This video shows that vaccines have helped some people with #longCOVID with their symptoms. While the numbers are still small in some groups, there are encouraging signs (also via @DanielGriffinMD). I present my hypothesis on how vaccines might improve #LongCovid (1/)”
Reverse-engineered by an external user, it seems: ‘This information below is gathered from sporadic developer posts and videos, salted with my own experience and experiments, various forum threads, and watching streams. Note that since Blizzard does not give exact algorithms, I do have to fill in some gaps, or leave some items unknown.’ The matchmaking systems are very complex and a key component of what makes games like Overwatch playable, so this is interesting stuff. (via Shevaun)
This is great. An amulet is ‘a kind of poem that depends on language, code, and luck. To qualify, a poem must satisfy these criteria: Its complete Unicode text is 64 bytes or less; and the hexadecimal SHA-256 hash of the text includes four or more 8s in a row.’
The hash is a cold hexadecimal spew – 9a120001cc88888363fc67c45f2c52447ae64808d497ec9d699dba0d74d72aab – and, like a fingerprint, it doesn’t tell you anything about the entity it identifies. That’s by design, but even so, it feels strange for a value so pivotal to be totally disconnected from the underlying content, especially when it is this value that’s being collected and traded in cryptographic marketplaces. Ostensibly, the hash provides an immutable link between unique cryptographic object and free-floating digital media. The amulet asks: what if we took that link seriously? In a sense, the definition of the SHA-256 hash function created, at a stroke, all amulets of all rarities. Common to mythic, trashy to lovely, they have been hiding in the manifold combinations of language; we just didn’t know we ought to be looking for them. Until now!
This is comedy gold. Turns out some digital phrenology software used for AI-aided interviewing will produce higher results for candidates who simply have a bookshelf as a background. As Daniel Bilar puts it: it’s the “Clever Hans” phenomenon, […] ‘spurious correlations, can occur when there is a feature in the data that is highly correlated with the correct outcome, but is not the cause for the answer being correct.’
Via Colman Reilly — this really sounds like outright fraudulent behaviour by FB:
The filing also reveals that a Facebook product manager for the “potential reach” tool warned the company was making revenue it “should never have” off of “wrong data”. The unsealed documents pertain to a U.S. class action lawsuit, filed in 2018, which alleges that Facebook deceived advertisers by knowingly including fake and duplicate accounts in a “potential reach” metric. Facebook denies the claim but has acknowledged accuracy issues with the “potential reach” metric as far back as 2016 — and also changed how it worked in 2019. […] Redacted documents from the lawsuit, reported by the WSJ last year, included the awkward detail that a Facebook employee had asked “how long can we get away with the reach overestimation?”
This is pretty solid real-world data, IMO — even if they’re not testing correctly to find it, it’s there in the ONS data
Testing people with any of the three ‘classic’ symptoms would have spotted 69% of symptomatic cases, with 46 people testing negative for every person testing positive. However, testing people with any of seven key symptoms – cough, fever, anosmia, fatigue, headache, sore throat and diarrhoea – in the first three days of illness would have detected 96% of symptomatic cases. In this case, for every person with the disease identified, 95 would test negative. Researchers also found users of the Symptom Study App were more likely to select headache and diarrhoea within the first three days of symptoms, and fever during the first seven days, which reflects different timings of symptoms in the disease course. Data from the ZOE app shows that 31% of people who are ill with COVID-19 don’t have any of the triad of symptoms in the early stages of the disease when most infectious.
working on the maths on outage probabilities.
via Paddy Mallon on twitter: ‘results (pre-print) of an analysis examining SARS-CoV-2 variants in Ireland from hospital cases during 2020. This is the largest analysis of its kind to date in Ireland and provides some important insights into #COVID19Ireland.”
1. Effective lockdown leading to low transmission rates can essentially eliminate common #SARS_CoV_2 variants contributing to disease ..BUT.. 2. ..new variants can be introduced (likely [via] travel) that seed new waves of #COVID19. As daily infections fall, hopefully correct implementation of new travel restrictions can help stop future W4 of #COVID19Ireland. We also hope that this data helps people understand how travel contributes to new #COVID19 infections (and new variants) coming into the country.
via John McClean: Imperial College COVID-19 Response Team report on premature reopening under different vaccination strategies in the UK. They find significant risk of a large 3rd wave of infections: ‘For all gradual easing of NPI scenarios explored, unless vaccination is rapidly ramped up to 3 million doses a week, gradual lifting of NPIs from 1st March to 1st July will lead to a third wave of hospitalisations which will exceed our indicative threshold of 25,000 beds national hospital capacity.’
Excellent article from Tomas Pueyo on the new COVID-19 variants:
In the race between the variants and the vaccines, the variants are the hare and the vaccines are the tortoise. We all know that, in the end, the vaccines will win. Like the tortoise. By this summer, in developed countries, vaccination rates will likely range between 50% and 80%. Since there will also be some herd immunity, and summer means outdoors in the Northern hemisphere, it’s likely that the pandemic will die down some time during the summer. The question is: Will they also be rolled out in time to prevent the new variants from taking over? Now we have our answer: Unfortunately, no.TBH, though, I am not so sanguine about the results for the Northern hemisphere. With open borders, no mandatory quarantine, and the rest of the world suffering without sufficient access to vaccines, new variants will keep passaging and keep emerging, risking putting our vaccine progress back to square one. (via Cormac)
Adam Kucharski on Twitter: “I’ve noticed people sometimes use ‘herd immunity’ to mean ‘pathogen fades to zero and stays there’ rather than the technical definition (i.e. R drops below 1 because of accumulated immunity, without NPIs). Why is the distinction important? ….”
I can confirm, zstd is awesome — must use xxHash more, too.
Newer Tar 1.32+ and Rsync 3.2.3 versions have added Facebook’s zstd compression algorithm and Rsync has added lz4 and xxHash checksum algorithms which give Tar and Rsync a tremendous boost in transfer speed.
significantly faster than Murmur3 and City32; SSE code is even faster than sequential RAM reads :)
Kai Kupferschmidt on Twitter: “Natural immunity: This was maybe the worst bit of news buried here. In the placebo group there were previously infected people and people that had not been infected. In the trial both groups ended up getting #covid19 with the same likelihood: 2%.”
Jaysus, this is terrifying.
Galvão, the lead physician in the coronavirus ward at a public hospital in the Brazilian city of Manaus, had been haunted by the wave that crashed last spring. In less than 10 days, it ruptured the city’s bewildered medical system. Sick patients were turned away. The dead were piled into mass graves. So Galvão’s hospital organized contingency plans. Additional beds were reserved, and a detailed schedule for opening them was created. But the new surge, when it came, was different. The virus had mutated, with a suite of alterations that probably made it more transmissible — and perhaps more lethal. Manaus was hit by what scientists call the P.1 variant. This time, it didn’t take 10 days to overwhelm Galvão’s hospital. It took 24 hours.
oh my, I didn’t realise you could jailbreak a Kindle and do this! Simple dashboard that HTTP fetches a rendered PNG periodically and refreshes the Kindle screen with it